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Panama & South America


Top Best Bets
  1. Top Pick

    Pacific Coastal & Panama Canal Cruise

    September 14 or 26, 2025
    18 or 24 night cruise aboard Serenade of the Seas or Radiance of the Seas
    Ports: itinerary varies
    Book from Nov 18-21: Exclusive book a Balcony and receive $225 USD onboard credit per cabin!

    from
    $1799 + $1123 tax
    18 or 24 nights meals
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  2. Top Pick

    Panama Canal Cruise

    October 11, 2025
    16 nights cruise aboard Carnival Spirit
    Ports: Seattle, Cabo San Lucas, Puntarenas, Panama Canal Transit, Cartagena, New Orleans
    Receive $25 USD onboard credit per cabin!

    from
    $1849 + $148 tax
    16 nights meals onboard credit
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  3. Top Pick

    Panama Canal & Pacific Coast

    April 13, 2025
    Air, 21 nights cruise aboard Caribbean Princess & transfer
    Ports: Port Canaveral (Orlando), Nassau, Cartagena, Panama Canal Full Transit, Fuerte Amador, Puntarenas, Huatulco, Puerto Vallarta, Los Angeles, San Francisco, Victoria, Vancouver

    from
    $1899 + $1128 tax
    airfare 21 nights transfer meals
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  4. Top Pick

    Panama Canal: Mexico & Costa Rica

    March 30, 2025
    21 nights cruise aboard Norwegian Encore
    Ports: Miami, Cartagena, Daylight Transit Panama Canal, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, Los Angeles, San Francisco (x2), Victoria, Seattle,
    Book by Nov 30: Exclusive $25 USD onboard credit per cabin, open bar, specialty dining, Wi-Fi & shore excursion credit!

    from
    $1979 + $977 tax
    21 nights meals open bar, dining, wi-fi, excursions credit onboard credit
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  5. Top Pick

    Panama Canal Cruise

    April 11, 2025
    Air, 20 nights cruise aboard Eurodam & transfer
    Ports: Fort Lauderdale, Cartagena, Panama Canal Cristobal, Puntarenas (Puerto Caldera), Puerto Quetzal, Huatulco, Puerto Vallarta, San Diego, San Francisco, Victoria, Vancouver
    Exclusive $75 USD onboard credit per cabin!

    from
    $2199 + $998 tax
    airfare 20 nights transfer meals onboard credit
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Cruise
Expedition Cruise: Galapagos Islands

January 29 – December 31, 2025
2 nights hotel in Quito, roundtrip airfare from Quito to Baltra, 6 nights expedition cruise aboard MS Santa Cruz II (Hurtigruten Expeditions), meals & beverages, WIFI, transfers and more
Ports: Quito (x2), Galápagos, Isabela and Fernandina Islands, Santa Cruz Island, Floreana Island, Baltra
Rates in USD.
Book by Dec 7: Reduced rates!

from
$6759
2 nights airfare 6 nights meals transfers
from
$6759
2 nights airfare 6 nights meals transfers
Premium: Panama Potpourri

March 22, 2025 (Oceanview)
Air, 10 nights cruise aboard Sirena (Oceania Cruises), transfers, prepaid gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: Miami, Great Stirrup Cay, Costa Maya, Santo Tomas, Belize City, Roatan, Puerto Limon, Panama City (x2)
Book by Dec 10: Black Friday Sale: Category Upgrade plus Choose One: Free Airfare, Beverage Package or $800 USD Onboard Credit!

from
$4429
10 nights prepaid gratuities unlimited wi-fi, specialty restaurants, laundry services & more
from
$4429
10 nights prepaid gratuities unlimited wi-fi, specialty restaurants, laundry services & more
Panama Canal: Mexico & Costa Rica

March 30, 2025
21 nights cruise aboard Norwegian Encore
Ports: Miami, Cartagena, Daylight Transit Panama Canal, Puntarenas, Puerto Quetzal, Puerto Vallarta, Cabo San Lucas, Los Angeles, San Francisco (x2), Victoria, Seattle,
Book by Nov 30: Exclusive $25 USD onboard credit per cabin, open bar, specialty dining, Wi-Fi & shore excursion credit!

from
$1979 + $977 tax
21 nights meals open bar, dining, wi-fi, excursions credit onboard credit
from
$1979 + $977 tax
21 nights meals open bar, dining, wi-fi, excursions credit onboard credit
Panama Canal & Pacific Coast

April 10, 2025
23 nights cruise aboard Coral Princess
Ports: Ft. Lauderdale, Aruba, Panama Canal Full Transit Historic, Fuerte Amador, Puntarenas, Puerto Chiapas, Huatulco, Puerto Vallarta, Los Angeles, San Diego, San Francisco, Astoria, Victoria, Vancouver
Exclusive $60 USD onboard credit per cabin!

from
$2269 + $1286 tax
23 nights meals onboard credit
from
$2269 + $1286 tax
23 nights meals onboard credit
Panama Canal Cruise

April 11, 2025
Air, 20 nights cruise aboard Eurodam & transfer
Ports: Fort Lauderdale, Cartagena, Panama Canal Cristobal, Puntarenas (Puerto Caldera), Puerto Quetzal, Huatulco, Puerto Vallarta, San Diego, San Francisco, Victoria, Vancouver
Exclusive $75 USD onboard credit per cabin!

from
$2199 + $998 tax
airfare 20 nights transfer meals onboard credit
from
$2199 + $998 tax
airfare 20 nights transfer meals onboard credit
Panama Canal Cruise

April 12, 2025
Air, 21 nights cruise aboard Nieuw Amsterdam & one way transfer
Ports: Fort Lauderdale, Grand Turk, Oranjestad (Aruba), Cartagena, Panama Canal (cruising only), Puntarenas, Acajutla, Puerto Vallarta, Cabo San Lucas, San Diego, Victoria, Vancouver
Exclusive $100 USD onboard credit per cabin!

from
$2199 + $998 tax
airfare transfer 21 nights meals onboard credit
from
$2199 + $998 tax
airfare transfer 21 nights meals onboard credit
Panama Canal & Pacific Coast

April 13, 2025
Air, 21 nights cruise aboard Caribbean Princess & transfer
Ports: Port Canaveral (Orlando), Nassau, Cartagena, Panama Canal Full Transit, Fuerte Amador, Puntarenas, Huatulco, Puerto Vallarta, Los Angeles, San Francisco, Victoria, Vancouver

from
$1899 + $1128 tax
airfare 21 nights transfer meals
from
$1899 + $1128 tax
airfare 21 nights transfer meals
Pacific Coastal & Panama Canal Cruise

September 14 or 26, 2025
18 or 24 night cruise aboard Serenade of the Seas or Radiance of the Seas
Ports: itinerary varies
Book from Nov 18-21: Exclusive book a Balcony and receive $225 USD onboard credit per cabin!

from
$1799 + $1123 tax
18 or 24 nights meals
from
$1799 + $1123 tax
18 or 24 nights meals
Deluxe Cruise: Panama Canal

September 21, 2025
21 night cruise aboard Queen Elizabeth (Cunard)
Ports: Seattle, San Francisco, Los Angeles, Cabo San Lucas, Puntarenas, Cartagena, Oranjestad, Miami
Exclusive $150 USD onboard credit per cabin!

from
$2599 + $915 tax
21 nights meals onboard credit
from
$2599 + $915 tax
21 nights meals onboard credit
Panama Canal Cruise

October 5, 2025
21 nights cruise aboard Eurodam
Ports: Vancouver, Santa Barbara, San Diego, Puerto Vallarta, Huatulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Puntarenas (Puerto Caldera), Cruising Panama Canal, Aruba, Fort Lauderdale
Exclusive $100 USD onboard credit per cabin!

from
$2599 + $965 tax
21 nights meals onboard credit
from
$2599 + $965 tax
21 nights meals onboard credit
Luxury Yacht Cruise: Rio de Janeiro to Buenos Aires

October 11, 2025
11 nights all-inclusive cruise aboard Scenic Eclipse, meals and beverages on board, butler service, shore excursions, gratuities and transfers
Ports: Rio de Janeiro, Búzios, Ilha Grande, Paraty, Ilhabela, Pontal do Sul, São Francisco do Sul, Punta del Este, Montevideo, Buenos Aires
Book by Dec 31: Save $5000 per cabin!

from
$12679
11 nights all inclusive transfers luxury
from
$12679
11 nights all inclusive transfers luxury
Panama Canal Cruise

October 11, 2025
16 nights cruise aboard Carnival Spirit
Ports: Seattle, Cabo San Lucas, Puntarenas, Panama Canal Transit, Cartagena, New Orleans
Receive $25 USD onboard credit per cabin!

from
$1849 + $148 tax
16 nights meals onboard credit
from
$1849 + $148 tax
16 nights meals onboard credit
Luxury Yacht Cruise: Antarctica in Depth

December 10, 2025
1 night pre-cruise hotel, domestic airfare, 11 night all-inclusive cruise aboard Scenic Eclipse, meals and beverages on board, butler service, shore excursions and transfers
Ports: Buenos Aires, Ushuaia, Antartica (x6), Ushuaia, Buenos Aires
Book by Dec 31: Save $9600 per cabin!

from
$24439
1 night domestic airfare 11 nights all inclusive luxury
from
$24439
1 night domestic airfare 11 nights all inclusive luxury
Premium: Amazon & Caribbean Gems

January 26, 2026
Air, 19 night cruise aboard Insignia (Oceania Cruises), transfers, prepaid gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: Bridgetown, Amazon River (Cruising), Santarem, Parintins,  Manaus (x2), Boca Da Valeria, Alter Do Chao, Amazon River (Cruising), Devil’s Island, Scarborough, Port of Spain, St. George’s, Kingstown, Castries, Bridgetown
Book by Dec 4: Bonus savings!

from
$8299
airfare 19 nights shuttle services prepaid gratuities unlimited wi-fi, specialty restaurants, laundry services & more
from
$8299
airfare 19 nights shuttle services prepaid gratuities unlimited wi-fi, specialty restaurants, laundry services & more
River Cruise
Magic of Colombia River Cruise

May 31, 2025
7 night deluxe river cruise aboard AmaMagdalen, meals & beverages, sightseeing and more
Ports: Baranquilla, Nueva Venecia, Santa Barbara de Pinto, Mompox (x2), El Banco, Magangue, Calamar, Cartagena Muelle, Cartagena Turistica

from
$5169 + $297 tax
7 nights meals & beverages sightseeing
from
$5169 + $297 tax
7 nights meals & beverages sightseeing
World Cruise
Premium: Around the World

December 20, 2025, January 6 or March 7, 2026
Air, 1 night pre-cruise hotel and 197, 180 or 120 nights cruise aboard Vista (Oceania Cruises), prepaid gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: varies
Exclusive FREE Claire Newell Travel Wallet plus Executive Prestige Package: shore excursion credit, house beverage package, onboard medical services, exclusive shoreside events, visa package & luggage delivery

from
$68269
airfare 197, 180 or 120 nights transfers prepaid gratuities unlimited wi-fi, specialty restaurants, laundry services & more
from
$68269
airfare 197, 180 or 120 nights transfers prepaid gratuities unlimited wi-fi, specialty restaurants, laundry services & more

Terms & Conditions

All rates are per person, based on double occupancy in Canadian dollars (unless otherwise stated) New bookings only. Space and price may be limited and subject to availability at the time of booking.  Errors or omissions may occur on the above information with no guarantee of being honoured. Terms and conditions apply. Tax is not included in the above base fare. Above tax amount includes non-refundable $30 per adult Booking Management Fee. $50 per adult cancellation fee. Not included in the above rates: Xpresspost fee, recommended medical, cancellation or baggage insurance. Child rate is applicable when travelling with 2 paying adults sharing 1 hotel room, using the existing bedding. Price Match Policy: Travel Best Bets makes every effort to remain competitive by offering our ‘Match or Beat Any Price’ offer however due to certain restrictions  there will be some product we cannot match or beat. Please note the star ratings found on www.travelbestbets.com are determined by Travel Best Bets based on a number of factors and may not match the star rating found in the Tour Operator’s brochure. Please view our star ratings by clicking here. Due to an increasing volume of disputed bookings, we will only accept payment for air only travel to India, the Philippines and the continent of Africa through the following means: book and pay cash in person or by direct deposit into our business account – once the transaction is verified and a copy of the receipt emailed or faxed to our office, we will confirm the booking. Please contact us for details on how to book using this method. Please contact [email protected] for photo credit information. BPCPA #3287