location icon telephone icon facebook icon twitter icon instagram icon
location icon mail icon

Panama & South America


Top Best Bets
  1. Top Pick

    Panama Canal Cruise

    April 12, 2025
    20 nights cruise aboard Eurodam
    Ports: Fort Lauderdale, Cartagena, Panama Canal Cristobal, Puntarenas (Puerto Caldera), Puerto Quetzal, Huatulco, Puerto Vallarta, San Diego, San Francisco, Victoria, Vancouver
    Exclusive $75 USD onboard credit per cabin!

    from
    $1489 + $985 tax
    20 nights meals onboard credit
    arrow
  2. Top Pick

    Panama Canal Cruise

    April 13, 2025
    21 nights cruise aboard Nieuw Amsterdam
    Ports: Fort Lauderdale, Grand Turk, Oranjestad (Aruba), Cartagena, Panama Canal (cruising only), Puntarenas, Acajutla, Puerto Vallarta, Cabo San Lucas, San Diego, Victoria, Vancouver
    Exclusive $100 USD onboard credit per cabin!

    from
    $1599 + $966 tax
    21 nights meals onboard credit
    arrow
  3. Top Pick

    Premium: Panama Canal

    September 21, 2025
    21 night cruise aboard Queen Elizabeth (Cunard)
    Ports: Seattle, San Francisco, Los Angeles, Cabo San Lucas, Puntarenas, Cartagena, Oranjestad, Miami
    Book by Jan 28: Exclusive $150 USD onboard credit per cabin!

    from
    $1729 + $982 tax
    21 nights meals onboard credit
    arrow
  4. Top Pick

    Pacific Coastal & Panama Canal Cruise

    September 14 or 26, 2025
    18 or 24 night cruise aboard Serenade of the Seas or Radiance of the Seas
    Ports: itinerary varies
    Book by Jan 27: Exclusive up to $300 USD onboard credit per cabin!

    from
    $1799 + $1123 tax
    18 or 24 nights meals
    arrow
  5. Top Pick

    Panama Canal & Pacific Coast

    April 14, 2025
    21 nights cruise aboard Caribbean Princess
    Ports: Port Canaveral (Orlando), Nassau, Cartagena, Panama Canal Full Transit, Fuerte Amador, Puntarenas, Huatulco, Puerto Vallarta, Los Angeles, San Francisco, Victoria, Vancouver

    from
    $1839 + $1016 tax
    21 nights meals
    arrow
Cruise
Premium: Panama Potpourri

March 23, 2025 (Oceanview)
10 nights cruise aboard Sirena (Oceania Cruises), gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: Miami, Great Stirrup Cay, Costa Maya, Santo Tomas, Belize City, Roatan, Puerto Limon, Panama City (x2)
Book by Jan 31: New Year Sale: Category Upgrade plus Choose One: Free Airfare, Beverage Package or Onboard Credit!

from
$4479
10 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
from
$4479
10 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
Panama Canal & Pacific Coast

April 10, 2025
23 nights cruise aboard Coral Princess
Ports: Ft. Lauderdale, Aruba, Panama Canal Full Transit Historic, Fuerte Amador, Puntarenas, Puerto Chiapas, Huatulco, Puerto Vallarta, Los Angeles, San Diego, San Francisco, Astoria, Victoria, Vancouver
Exclusive $60 USD onboard credit per cabin!

from
$2339 + $1286 tax
23 nights meals onboard credit
from
$2339 + $1286 tax
23 nights meals onboard credit
Panama Canal Cruise

April 12, 2025
20 nights cruise aboard Eurodam
Ports: Fort Lauderdale, Cartagena, Panama Canal Cristobal, Puntarenas (Puerto Caldera), Puerto Quetzal, Huatulco, Puerto Vallarta, San Diego, San Francisco, Victoria, Vancouver
Exclusive $75 USD onboard credit per cabin!

from
$1489 + $985 tax
20 nights meals onboard credit
from
$1489 + $985 tax
20 nights meals onboard credit
Panama Canal Cruise

April 13, 2025
21 nights cruise aboard Nieuw Amsterdam
Ports: Fort Lauderdale, Grand Turk, Oranjestad (Aruba), Cartagena, Panama Canal (cruising only), Puntarenas, Acajutla, Puerto Vallarta, Cabo San Lucas, San Diego, Victoria, Vancouver
Exclusive $100 USD onboard credit per cabin!

from
$1599 + $966 tax
21 nights meals onboard credit
from
$1599 + $966 tax
21 nights meals onboard credit
Panama Canal & Pacific Coast

April 14, 2025
21 nights cruise aboard Caribbean Princess
Ports: Port Canaveral (Orlando), Nassau, Cartagena, Panama Canal Full Transit, Fuerte Amador, Puntarenas, Huatulco, Puerto Vallarta, Los Angeles, San Francisco, Victoria, Vancouver

from
$1839 + $1016 tax
21 nights meals
from
$1839 + $1016 tax
21 nights meals
Expedition Cruise: Galapagos Islands

May 7 – June 18, 2025
2 nights hotel in Quito, roundtrip airfare from Quito to Baltra, 6 nights expedition cruise aboard MS Santa Cruz II (Hurtigruten Expeditions), meals & beverages, WIFI, transfers and more
Ports: Quito (x2), Galápagos, Isabela and Fernandina Islands, Santa Cruz Island, Floreana Island, Baltra
Rates in USD.
Book by Mar 31: Reduced rates!

from
$7869
2 nights airfare 6 nights meals transfers
from
$7869
2 nights airfare 6 nights meals transfers
Pacific Coastal & Panama Canal Cruise

September 14 or 26, 2025
18 or 24 night cruise aboard Serenade of the Seas or Radiance of the Seas
Ports: itinerary varies
Book by Jan 27: Exclusive up to $300 USD onboard credit per cabin!

from
$1799 + $1123 tax
18 or 24 nights meals
from
$1799 + $1123 tax
18 or 24 nights meals
Premium: Panama Canal

September 21, 2025
21 night cruise aboard Queen Elizabeth (Cunard)
Ports: Seattle, San Francisco, Los Angeles, Cabo San Lucas, Puntarenas, Cartagena, Oranjestad, Miami
Book by Jan 28: Exclusive $150 USD onboard credit per cabin!

from
$1729 + $982 tax
21 nights meals onboard credit
from
$1729 + $982 tax
21 nights meals onboard credit
Panama Canal Cruise

October 5, 2025
21 nights cruise aboard Eurodam
Ports: Vancouver, Santa Barbara, San Diego, Puerto Vallarta, Huatulco, Puerto Chiapas, Puerto Quetzal, Acajutla, Puntarenas (Puerto Caldera), Cruising Panama Canal, Aruba, Fort Lauderdale
Exclusive $100 USD onboard credit per cabin!

from
$2259 + $1012 tax
21 nights meals onboard credit
from
$2259 + $1012 tax
21 nights meals onboard credit
Luxury Yacht Cruise: Rio de Janeiro to Buenos Aires

October 11, 2025 (Deluxe Verandah)
11 nights all-inclusive cruise aboard Scenic Eclipse, meals and beverages on board, butler service, shore excursions, gratuities and transfers
Ports: Rio de Janeiro, Búzios, Ilha Grande, Paraty, Ilhabela, Pontal do Sul, São Francisco do Sul, Punta del Este, Montevideo, Buenos Aires
Hosted by Tom Götter, Scenic VP of Oceans Hotel Operations and Chef Luciana Berry
Book by Mar 31: Save up to $10000 per cabin!

from
$16359
11 nights all inclusive transfers luxury culinary expedition
from
$16359
11 nights all inclusive transfers luxury culinary expedition
Panama Canal Cruise

October 11, 2025
16 nights cruise aboard Carnival Spirit
Ports: Seattle, Cabo San Lucas, Puntarenas, Panama Canal Transit, Cartagena, New Orleans
Book by Jan 31: Receive $25 USD onboard credit per cabin!

from
$1849 + $150 tax
16 nights meals onboard credit
from
$1849 + $150 tax
16 nights meals onboard credit
Panama Canal: Mexico & Costa Rica

October 19, 2025
20 nights cruise aboard Norwegian Encore
Ports: Seattle, San Francisco, Los Angeles, Cabo San Lucas, Puerto Vallarta, Manzanillo, Acapulco, Puerto Quetzal, Puntarenas (Puerto Caldera), Panama City (Pacific Cruise Terminal), Cartagena, Miami
Exclusive $25 USD onboard credit per cabin, open bar, specialty dining, Wi-Fi & shore excursion credit!

from
$2199 + $990 tax
20 nights meals open bar, dining, wi-fi, excursions credit onboard credit
from
$2199 + $990 tax
20 nights meals open bar, dining, wi-fi, excursions credit onboard credit
Luxury Yacht Cruise: Antarctica in Depth

November 10 or December 9, 2025
Air, 1 night pre-cruise hotel, 11 night all-inclusive cruise aboard Scenic Eclipse, meals and beverages on board, butler service, shore excursions and transfers
Ports: Buenos Aires, Ushuaia, Antartica (x6), Ushuaia, Buenos Aires
Book by Mar 31: FREE Air!

from
$29239
airfare 1 night 11 nights all inclusive luxury
from
$29239
airfare 1 night 11 nights all inclusive luxury
Premium: Panama Canal, Maya & Inca Discovery

November 29, 2025 (Balcony)
22 nights cruise aboard Marina (Oceania Cruises), gratuities, unlimited Wi-Fi,  specialty restaurants, laundry services & more
Ports: Miami, Cozumel, Costa Maya, Belize City, Harvest Caye, Santo Tomas, Roatan, Puerto Limon, Panama Canal (Cruising), Panama City (x2), Manta, Guayaquil, Salaverry, Lima/Machu Picchu (Callao), Coquimbo, Santiago de Chile (San Antonio) (x2)
Book by Jan 31: New Year Sale: Category Upgrade plus Choose One: Reduced Airfare, Beverage Package or Onboard Credit!

from
$9729
22 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
from
$9729
22 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
Premium: Around the World

December 20, 2025, January 6 or March 7, 2026
Air, 1 night pre-cruise hotel and 197, 180 or 120 nights cruise aboard Vista (Oceania Cruises), gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: varies
Exclusive FREE Claire Newell Travel Wallet plus Executive Prestige Package: shore excursion credit, house beverage package, onboard medical services, exclusive shoreside events, visa package & luggage delivery

from
$68269
airfare 197, 180 or 120 nights transfers gratuities unlimited wi-fi, specialty restaurants, laundry services & more
from
$68269
airfare 197, 180 or 120 nights transfers gratuities unlimited wi-fi, specialty restaurants, laundry services & more
Premium: Chilean Fjords & The Antarctic Peninsula

December 21, 2025 (Balcony)
20 nights cruise aboard Marina (Oceania Cruises), gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: Santiago de Chile (San Antonio), Puerto Montt, Castro, Puerto Chacabuco, Laguna San Rafael, the Chilean Fjords (x2), Punta Arenas, Ushuaia, the Antarctic Peninsula (x3), Port Stanley, Puerto Madryn, Buenos Aires
Book by Jan 31: New Year Sale: Category Upgrade and Receive $250 USD Onboard Credit Per Cabin, plus Choose One: Reduced  Airfare, Beverage Package or Onboard Credit!

from
$9879
20 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
from
$9879
20 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
Premium: Amazon & Caribbean Gems

January 26, 2026
19 night cruise aboard Insignia (Oceania Cruises), gratuities, unlimited Wi-Fi, specialty restaurants, laundry services & more
Ports: Bridgetown, Amazon River (Cruising), Santarem, Parintins,  Manaus (x2), Boca Da Valeria, Alter Do Chao, Amazon River (Cruising), Devil’s Island, Scarborough, Port of Spain, St. George’s, Kingstown, Castries, Bridgetown

from
$7179
19 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
from
$7179
19 nights gratuities unlimited wi-fi specialty restaurants laundry services & more
River Cruise
Magic of Colombia River Cruise

June 11 – August 6, 2025
7 night deluxe river cruise aboard AmaMagdalen, meals & beverages, sightseeing and more
Ports: Baranquilla, Nueva Venecia, Santa Barbara de Pinto, Mompox (x2), El Banco, Magangue, Calamar, Cartagena Muelle, Cartagena Turistica
Save up to $1800 per cabin!

from
$3799 + $298 tax
7 nights meals & beverages sightseeing
from
$3799 + $298 tax
7 nights meals & beverages sightseeing

Terms & Conditions

All rates are per person, based on double occupancy in Canadian dollars (unless otherwise stated) New bookings only. Space and price may be limited and subject to availability at the time of booking.  Errors or omissions may occur on the above information with no guarantee of being honoured. Terms and conditions apply. Tax is not included in the above base fare. Above tax amount includes non-refundable $30 per adult Booking Management Fee. $50 per adult cancellation fee. Not included in the above rates: Xpresspost fee, recommended medical, cancellation or baggage insurance. Child rate is applicable when travelling with 2 paying adults sharing 1 hotel room, using the existing bedding. Price Match Policy: Travel Best Bets makes every effort to remain competitive by offering our ‘Match or Beat Any Price’ offer however due to certain restrictions  there will be some product we cannot match or beat. Please note the star ratings found on www.travelbestbets.com are determined by Travel Best Bets based on a number of factors and may not match the star rating found in the Tour Operator’s brochure. Please view our star ratings by clicking here. Due to an increasing volume of disputed bookings, we will only accept payment for air only travel to India, the Philippines and the continent of Africa through the following means: book and pay cash in person or by direct deposit into our business account – once the transaction is verified and a copy of the receipt emailed or faxed to our office, we will confirm the booking. Please contact us for details on how to book using this method. Please contact [email protected] for photo credit information. BPCPA #3287