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The Panama Canal is one of the most astonishing human-made wonders, a sliver of ingenuity that allows ships to move from one ocean to another. Cruise from the Pacific to the Atlantic, and take in the scenery as you move through this engineering marvel built in 1914. Along with the tropical views and modern design of the canal, there’s also great opportunity for adventures on land and by the shore, where you can get in touch with the indigenous culture by visiting a Mayan ruin in Mexico, or go kayaking in Nicoya Bay at Puntarenas, Costa Rica.

Inclusions
  • 18 or 24 night cruise aboard Serenade of the Seas or Radiance of the Seas
    (September 14, 2025: 5 nights Vancouver to San Diego & 13 nights San Diego to Miami)
    (September 26, 2025: 8 nights Vancouver to San Diego & 16 nights San Diego to Fort Lauderdale)
Cruise Only September 14, 2025
18 nights
Serenade of the Seas
September 26, 2025
24 nights
Radiance of the Seas
Inside $1879 $1799
Oceanview $2409 sold out
Balcony $3199 sold out
Taxes & Fees $1168 $1123
Please note that this cruise is a back-to-back sailing. Every effort will be made to assign the same cabin number for all sailings; however, it is not guaranteed as it is based on availability at the time of booking.

 

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Serenade of the Seas – 18 nights
Date Ports of Call Arrival Time Departure Time Activity
Sun 14Sep2025 Vancouver, British Columbia 5:00 PM Boarding
Mon 15Sep2025 Seattle, Washington 7:00 AM 4:00 PM Docked
Tue 16Sep2025 Astoria, Oregon 9:30 AM 5:00 PM Docked
Wed 17Sep2025 Cruising Cruising
Thu 18Sep2025 Cruising Cruising
Fri 19Sep2025 San Diego, California 7:00 AM Departure
Date Ports of Call Arrival Time Departure Time Activity
Fri 19Sep2025 San Diego, California 5:00 PM Boarding
Sat 20Sep2025 Cruising Cruising
Sun 21Sep2025 Cruising Cruising
Mon 22Sep2025 Puerto Vallarta, Mexico 7:00 AM 4:00 PM Docked
Tue 23Sep2025 Cruising Cruising
Wed 24Sep2025 Huatulco, Mexico 8:00 AM 4:00 PM Docked
Thu 25Sep2025 Cruising Cruising
Fri 26Sep2025 Puntarenas, Costa Rica 12:30 PM 8:00 PM Docked
Sat 27Sep2025 Cruising Cruising
Sun 28Sep2025 Panama Canal, Panama 6:00 AM 3:00 PM Cruising
Mon 29Sep2025 Cartagena, Colombia 8:00 AM 4:00 PM Docked
Tue 30Sep2025 Cruising Cruising
Wed 01Oct2025 Cruising Cruising
Thu 02Oct2025 Miami, Florida 5:00 AM Departure

Radiance of the Seas – 24 nights
Date Ports of Call Arrival Time Departure Time Activity
Fri 26Sep2025 Vancouver, British Columbia 4:00 PM Boarding
Sat 27Sep2025 Astoria, Oregon 11:30 AM 7:00 PM Docked
Sun 28Sep2025 Cruising Cruising
Mon 29Sep2025 San Francisco, California 10:00 AM Docked
Tue 30Sep2025 San Francisco, California 8:00 PM Docked
Wed 01Oct2025 Cruising Cruising
Thu 02Oct2025 Cruising Cruising
Fri 03Oct2025 Catalina Island, California 8:00 AM 5:00 PM Tendered
Sat 04Oct2025 San Diego, California 7:00 AM Departure
Date Ports of Call Arrival Time Departure Time Activity
Sat 04Oct2025 San Diego, California 4:00 PM Boarding
Sun 05Oct2025 Cruising Cruising
Mon 06Oct2025 Cabo San Lucas, Mexico 11:59 AM 8:00 PM Tendered
Tue 07Oct2025 Mazatlan, Mexico 8:00 AM 5:00 PM Docked
Wed 08Oct2025 Cruising Cruising
Thu 09Oct2025 Cruising Cruising
Fri 10Oct2025 Puerto Quetzal, Guatemala 9:00 AM 6:00 PM Docked
Sat 11Oct2025 Cruising Cruising
Sun 12Oct2025 Puntarenas, Costa Rica 8:00 AM 6:00 PM Docked
Mon 13Oct2025 Cruising Cruising
Tue 14Oct2025 Panama Canal, Panama 6:00 AM 6:00 PM Cruising
Wed 15Oct2025 Colon, Panama 7:00 AM 4:00 PM Docked
Thu 16Oct2025 Cartagena, Colombia 9:00 AM 6:00 PM Docked
Fri 17Oct2025 Cruising Cruising
Sat 18Oct2025 George Town, Grand Cayman 7:00 AM 4:00 PM Tendered
Sun 19Oct2025 Cruising Cruising
Mon 20Oct2025 Fort Lauderdale, Florida 6:00 AM Departure

 

 

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Shore Excursions Group
Add Shore Excursions to your cruise booking today!

 

Terms & Conditions

All rates are per person, based on double occupancy in Canadian dollars (unless otherwise stated) New bookings only. Space and price may be limited and subject to availability at the time of booking.  Errors or omissions may occur on the above information with no guarantee of being honoured. Terms and conditions apply. Tax is not included in the above base fare. Above tax amount includes non-refundable $30 per adult Booking Management Fee. $50 per adult cancellation fee. Not included in the above rates: Xpresspost fee, recommended medical, cancellation or baggage insurance. Child rate is applicable when travelling with 2 paying adults sharing 1 hotel room, using the existing bedding. Price Match Policy: Travel Best Bets makes every effort to remain competitive by offering our ‘Match or Beat Any Price’ offer however due to certain restrictions  there will be some product we cannot match or beat. Please note the star ratings found on www.travelbestbets.com are determined by Travel Best Bets based on a number of factors and may not match the star rating found in the Tour Operator’s brochure. Please view our star ratings by clicking here. Due to an increasing volume of disputed bookings, we will only accept payment for air only travel to India, the Philippines and the continent of Africa through the following means: book and pay cash in person or by direct deposit into our business account – once the transaction is verified and a copy of the receipt emailed or faxed to our office, we will confirm the booking. Please contact us for details on how to book using this method. Please contact [email protected] for photo credit information. BPCPA #3287